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Articles tagged open science

  1. Things I'm Glad I Learned

    Skills, concepts, techniques, and models

    WARNING: This post was written with haste and therefore contains all kinds of typos, spelling errors, grammatical issues, and delusions of grandeur, wisdom, and writing ability.

    This post is intended as a living document—a gratitude journal of sorts—of some things that I'm glad I learned. I expect many of the items on this list will be relevant to computation biology, but that may change in the future.

    The big idea is that for every item on this list I am (A) glad that someone introduced me to it, and (B) think more people should know about it. This post is my chance to "pay it backwards", as it were; maybe someone else will be grateful for something they find for the first time on this list.

    It may also double as an inspiration list for future posts.

    My goal is to write a small blurb for each item …

  2. Changes to the gut microbiome resulting from acarbose treatment are associated with increased longevity in mice

    New preprint posted to the bioRxiv

    I'm excited to announce that we've posted a preprint of our latest manuscript to the bioRxiv, as well as submitted it for peer review to the open access journal Microbiome. I'll update this note if and when it gets accepted.

    Edit 2019-06-20: Our submission to Microbiome was tranferred to BMC Microbiology, and was finally accepted (more than a full year in review!). Check it out in print.

    These days it seems like the only research more over-hyped than "microbiome" is longevity-enhancement. It is therefore with some trepidation that I have released into this world of buzz the first chapter of my dissertation, titled: "Changes in the gut microbiota and fermentation products associated with enhanced longevity in acarbose-treated mice."

    Previous work (done by my co-authors on this paper as well as others) has conclusively demonstrated that treatment with the anti-diabetic drug acarbose substantially increases lifespan in mice (also). The magnitude of …

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